Tretizen-20 (Isotretinoin) is one of the most effective drugs for the treatment of acne and other skin diseases accompanied by hyperplasia of the sebaceous glands (rosacea, etc.). It belongs to the group of synthetic retinoids.
Isotretinoin is a form of vitamin A. It reduces the amount of sebum produced by the sebaceous glands and accelerates the skin's natural regeneration. It is used to treat severe acne that does not respond to other medications, including antibiotics.
With systematic use, the drug can improve skin regeneration processes. The mechanism of action is based on the ability to influence the composition of sebum, reduce its production and ensure rapid excretion from the sebaceous glands. Isotretinoin has an anti-inflammatory effect that aims to reduce inflammation around the glands in acne. It also has a pronounced keratolytic effect, which provides for the normalization of cell renewal and prevents sebaceous glands from blocking.
When taken, there is a suppression of the production of the sebaceous glands, the narrowing of the ducts and a decrease in their number. The drug is used even in cases where other means could not solve the problem. With its help, acne diseases that have not been eliminated by other drugs are treated, nodules, conglobata and acne, which can leave scars.
Among bodybuilders, doses should be conservative. A daily dose of 20mg for 6-8 weeks is an excellent choice. In addition to the direct action against acne, doses of 40-140mg can be prescribed by healthcare professionals. This drug is advised to be taken with a large intake of food. In addition, several cycles of this treatment are likely to be required.